SYSTEMS NEUROPSYCHIATRY & NEUROENGINEERING

The Systems Neuropsychiatry and Neuroengineering Research Stream aims to understand how different parts of the human brain interact with each other to produce complex behaviour and why these astoundingly complex interactions breakdown in individuals with serious mental illness. We model the brain in both health and disease using networks of interconnected neural elements that interact in time and space across a hierarchy of scales. Members develop new methodologies to perform statistical inference on brain networks and undertake research into computational models that describe the emergence and progression of network pathology over the course of disease. We aim to discover new ways to prevent, treat and cure mental illness. This stream brings together a diverse range of expertise from basic science, engineering and psychiatry in order to tackle these aims using innovative, interdisciplinary approaches.

Ye Tian (PhD Candidate)

MEMBERS:

Dr Jinglei Lv (Research Fellow)

Dr Maria DiBiase (Research Fellow)

Caio Seguin (PhD Candidate)

Sina Masour (PhD Candidate)

Xin Wang (PhD Candidate)

Dr Robin Cash (Research Fellow)

SIBLING STUDY

Information to come.

Funding: NHMRC Project Grant (ID 1161897)

Collaborators: 

Cropley VL, Klauser P, Lenroot RK, Bruggemann J, Sundram S, Bousman C, Pereira A, Di Biase MA, Weickert TW, Weickert CS, Pantelis C, Zalesky A (2017) Accelerated gray and white matter deterioration with age in schizophrenia. American Journal of Psychiatry. 174(3):286-295.

Sotiropoulos S, Zalesky A (2017) Building connectomes using diffusion MRI: why, how and but. NMR in Biomedicine.

Fornito A, Zalesky A, Bullmore E. (2016). Fundamentals of Brain Network Analysis, Academic Press (Elsevier). 450+ page authored textbook. Resides in top-10% most read neuroscience books published by Elsevier in 2016.

Zalesky A et al., (2014). Time-resolved resting-state brain networks. Proc Natl Acad Sci U S A 111, 10341-10346.

Zalesky A et al., (2012). Effects of long term cannabis use on axonal fibre connectivity. Brain 135, 2245-2255.

Fornito A, Zalesky A, Breakspear M. (2015). The connectomics of brain disorders. Nature Reviews Neuroscience 16, 159-172.

Zalesky A et al., (2015). Delayed development of brain connectivity in adolescents with schizophrenia and their unaffected siblings. JAMA Psychiatry 72; 900-908.

KEY PUBLICATIONS

Melbourne

Neuropsychiatry

Centre

University of Melbourne and

Melbourne Health

Melbourne Neuropsychiatry Centre

Level 3, Alan Gilbert Building

161 Barry Street

Carlton, Victoria, 3053

AUSTRALIA